Meet our investigators
Stephanie Seminara, MD, FACP
Program Director, MGH-Harvard Center for Reproductive Medicine
Dr. Seminara is a doctor who specializes in helping adults with hormone-related issues (endocrinologist). She is an expert in reproductive health and has been doing research for more than 25 years. Her research focuses on studying the genes and pathways in the brain that control the onset of puberty and fertility in both women and men.
Ming Chan, MD, PhD
Principal Investigator, MGH-Harvard Center for Reproductive Medicine
Dr. Chan is a doctor who specializes in treating children and adolescents with hormone-related conditions (pediatric endocrinologist). He is an expert in puberty and a scientist who studies how genetic information (genomics) affects health conditions in children and young adults.
Ravikumar Balasubramanian, MBBS, PhD, FRCPEdin
Assistant Director, MGH-Harvard Center for Reproductive Medicine
Dr. Balasubramanian is a doctor who specializes in helping adults with hormone-related issues (endocrinologist). He is also a scientist who studies genes that control reproduction, particularly in people who have certain reproductive disorders (syndromic hypogonadism).
Margaret F. Lippincott, MD
Co-Investigator, MGH-Harvard Center for Reproductive Medicine
Dr. Lippincott is a doctor who specializes in infertility and reproductive health (endocrinologist). She studies how changes in our genes can affect a person's risk of having problems with their fertility or reproductive system. Her goal is to improve the ways we diagnose and treat people who are struggling with infertility.
Corrine Kolka Welt, MD
Co-Investigator, MGH-Harvard Center for Reproductive Medicine
Dr. Welt is a doctor who specializes in helping adults with hormone-related issues (endocrinologist). She is an expert in female infertility and studies genes involved in female reproductive disorders (primary ovarian insufficiency and polycystic ovary syndrome).
Andrew Dwyer, PhD, FNP-BC, FNAP, FAAN
Principal Investigator, MGH-Harvard Center for Reproductive Medicine
Dr. Dwyer is a nurse practitioner who specializes in helping people with hormone-related issues (endocrinology). He studies how people cope with reproductive disorders and rare diseases. He works with patients to create person-centered approaches to care and to overcome health disparities.
Michael E. Talkowski, PhD
Principal Investigator, MGH-Harvard Center for Reproductive Medicine
Dr. Talkowski is the Director of the Center for Genomic Medicine, which is one of the largest centers for studying how genes affect human health. His lab works to understand how differences in our genes can lead to health problems. He specializes in problems with the development of the nervous system (called neurodevelopmental diseases).
Harrison Brand, PhD
Co-Investigator, MGH-Harvard Center for Reproductive Medicine
Dr. Brand leads the Structural Variation team in the Center for Genomic Medicine. He uses computer analysis of genes to better understand the genetic causes of diseases that are present at birth and conditions causing fertility problems. He has been working closely with the P50 Center for almost ten years.
Xuefang Zhao, PhD
Instructor in Neurology, Massachusetts General Hospital and Harvard Medical School
Dr. Zhao is a member of the Structural Variation team in the Center for Genomic Medicine. She studies new ways to find changes in DNA and connect structural changes in DNA with different health conditions in humans. She also studies how these changes affect the function of genes using RNA expression data.
Derek Jui-Cheng Tai, PhD
Instructor of Neurology, Massachusetts General Hospital and Harvard Medical School
Dr. Tai directs the Molecular Genomics team in the Center for Genomic Medicine. They study new ways to modify genes (CRISPR). They also study how to change skin or blood cells back to a stage similar to when they were first created (induced pluripotent stem cells, iPSC). The iSPC can be turned into any type of human cell that can be used for medical treatments.
Celine de Esch, PhD
Director, Genomics & Technology Core, Center for Genomic Medicine, Massachusetts General Hospital
Dr. de Esch directs the Genomics and Technology Core in the Center for Genomic Medicine which offers sequencing and computer services (bioinformatics) to research programs around the world. She is a scientist who uses human stem cells to study diseases that affect the development of the nervous system (called neurodevelopmental diseases).
Serkan Erdin, PhD
Director, Bioinformatics, Center for Genomic Medicine, Massachusetts General Hospital
Dr. Erdin directs Bioinformatics in the Center for Genomic Medicine. He is a scientist who uses computers and biological knowledge (computational biology and bioinformatics) to study genes and how they function. He also uses cells to study how the number of gene copies affect the development of the nervous system (neurodevelopmental disorders).